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Daedalus
  • Daedalus

Daedalus

An open-source Nintendo 64 emulator for Windows, OS X, and PSP.

Its source code is available on GitHub.

  • Fuse

Fuse

A Mac OS X port of The Free Unix Spectrum Emulator (Fuse) (an emulator of the 1980s home computer and various clones).

Sixtyforce
  • Author: Gerrit Goossen
  • Sixtyforce

Sixtyforce

From its official website:

sixtyforce is an emulator that runs Nintendo 64 games. It does this by dynamically translating the code that a Nintendo 64 uses into something your Mac understands. Nearly every part of a Nintendo 64 has been painstakingly recreated entirely out of software to pull off such an amazing feat. Download sixtyforce and try it yourself!

One of the better options for Mac users looking to emulate the Nintendo 64, Sixtyforce unfortunately receives irregular updates.

See here for the compatibility list.

OpenEmu
  • Author: OpenEmu Team
  • OpenEmu

OpenEmu

OpenEmu is an open source project to bring game emulation to OS X as a first class citizen, leveraging modern OS X technologies such as Cocoa, Core Animation and Quartz, and 3rd party libraries like Sparkle for auto-updating. OpenEmu is based on a modular architecture, allowing for game emulators as plugins, this means OpenEmu can support a host of different emulation engines and back-ends while retaining a familiar OS X native front-end.

Our sister site, Archive.vg, talked to the OpenEmu team for a feature article on how they hope to bring emulation to the masses.

DeSmuME
  • Author: DeSmuME Team
  • DeSmuME

DeSmuME

DeSmuME is software that allows you to emulate a Nintendo DS system. Think of it as a Swiss-Army knife for Nintendo DS emulation, giving you access to many powerful tools for testing DS features, from viewing ROM properties to managing Action Replay cheats. And best of all, this software is completely free and open-source.

Kega Fusion
  • Author: Steve Snake
  • Kega Fusion

Kega Fusion

Kega Fusion is an accuracy-focused emulator of multiple Sega systems, created by Steve Snake.

  • TwoMbit

TwoMbit

TwoMbit is a cycle-accurate emulator for Sega's 8-bit game consoles, the Master System, Game Gear, and SG-1000.

  • Author: James M. Reneau
  • FAUX1

FAUX1

FAUX1 is an Apple I emulator for the Terminal with full cut and paste. It was forked from napple1 and pom1.

  • Author: Frode Solheim
  • FS-UAE

FS-UAE

FS-UAE is a multi-platform Amiga emulator with a focus on games. It's a newcomer to the scene, first released in February 2012, and it uses WinUAE as a codebase.

MultiPatch
  • Author: Paul Kratt
  • MultiPatch

MultiPatch

MultiPatch is an all-in-one patching tool for Mac OS X. It allows users to create or apply IPS, UPS, PPF, XDelta, or BSDiff patches.

  • micro64

micro64

Micro64 aims to be the most accurate Commodore 64 emulator available. It's still in the pre-alpha stages of development, but work is progressing quickly.

  • Previous

Previous

Previous aims to emulate the NeXTcube and NeXTstation, with all associated peripherals. It is still in the early stages of development.

  • Author: Gerard Putter
  • Virtual ][

Virtual ][

A shareware Apple II, II+, and //e emulator for Mac OS X 10.6 or later. Virtual ][ offers many advanced features, including state saving and configurable peripheral cards.

Q-emuLator
  • Author: Daniele Terdina
  • Q-emuLator

Q-emuLator

A commercial Sinclair QL emulator for Intel Macs running OS X 10.5 or later.

OpenEmulator
  • OpenEmulator

OpenEmulator

OpenEmulator, which is not to be confused with Open Emu, is a component/framework-based emulator of legacy computer systems. It currently supports only the Apple I computer and its peripherals, although Apple II emulation is also planned.